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Wednesday, February 13, 2008

Cleaning Eudragit L 100 -55 with Solujet in a CSP Tank (Solution Preparation Tank)

Question:
What is the correct temperature needed to successfully clean Eudragit L 100-55 with Solujet in a CSP tank (Solution Preparation Tank)?

Answer:
It is recommended to clean with 1% Solujet at 40 deg C for 20 minutes. However, if only normal temperature (20 deg C) water is available, then theoretically it will take 4 times longer because every 10 deg C you go down in temperature doubles the cleaning time needed. If at all possible, it is preferred that cleaning be done with 40 deg C solutions. It is certainly worth trying to clean longer if using hotter solution is not possible. Raising the concentration of Solujet to 2% might help a little bit, but it should not be required.

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